The main effects of almost all ‘psychoactive’ drugs, including ‘legal highs’, can be described using three main categories:

Herbal Highs:

• Datura may cause severe, long-lasting disorientation, confusion, delirium, and hallucinations. Accidents and self-injuries, sometimes requiring hospitalization, are alarmingly frequent among datura users.
• Datura alkaloids can have toxic effects, including coma or death. 4-5 g of dried Datura stramonium leaves can contain a lethal dose of alkaloids, while flowers and seeds are considerably more potent.

• Pupil dilation and extreme thirst are usually the first symptoms, followed by hallucinations, elevated body temperature and increased heartbeat, or tachycardia.
• The hallucinations brought on by datura use differ from those caused by drugs such as LSD. A datura user is unable to distinguish between the hallucination and reality, a condition known as frank delirium.

• Datura is a woody-stalked, leafy herb growing up to 2 meters. It produces spiney seed pods and large white or purple trumpet-shaped flowers that face upward.
• Most parts of the plant contain atropine, scopolamine, and hyoscyamine.
• Datura has a long history of use both in S. America and Europe and is known for causing delirious states and poisonings in uninformed users.
• Users usually boil the seeds and flowers into tea and drink the mixture.