Drugs Information

Cocaine Tolerance (dependence) & withdrawal

  • Cocaine is a powerfully addictive drug of abuse and an appreciable initial tolerance to the euphoric high may develop.
  • They may also develop a tolerance to cocaine, which means they will need to use larger amounts to get the same effect.
  • Dependence on cocaine can be psychological, physical or both. People who are dependent crave cocaine and find it very difficult to stop using it.
  • People who are psychologically dependent on cocaine may feel an urge to use it when they are in specific situations.

Cocaine Duration of effect & 'come down' (half-life)

  • The faster the absorption the more intense and rapid the high, but the shorter the duration of action.
  • Injecting cocaine produces an effect within 15-30 seconds.
  • A hit of smoked crack produces an almost immediate intense experience and will typically produce effects lasting 5-15 minutes.
  • Similarly, snorting cocaine produces effects almost immediately and the resulting high may last 15-30 minutes.
  • The effects onset more slowly after oral ingestion (~1 hour).

Cocaine Route of administration & onset

  • Cocaine hydrochloride is most commonly snorted.
  • It can also be injected.
  • It can be rubbed into the gums where it is absorbed into the bloodstream. It can be added to a drink or food.
  • Freebase and crack cocaine are usually smoked.

Onset

  • The effects of cocaine can last anywhere from a few minutes to a couple of hours, depending on how it is taken. When the immediate “rush” of the cocaine has worn off, the individual may experience a “crash”.

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